Pitavastatin
Catalog No.
B1124
HMG-CoA reductase inhibitor
Featured Products
Pitavastatin (NK-104) is a potent HMG-CoA reductase inhibitor, Pitavastatin inhibited cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in a human liver cancer cell line (HepG2).
- 1. Brittany C S Ellis, Anna Sanchez Avila, et al. "STMN2 protein depletion via translation deficits and stress granules in amyotrophic lateral sclerosis." Brain. 2026 Jun 25:awag222. PMID: 42343570
- 2. Jie Yang, Mengjia Sun, et al. "Pitavastatin activates mitophagy to protect EPC proliferation through a calcium-dependent CAMK1-PINK1 pathway in atherosclerotic mice." Commun Biol. 2022 Feb 10;5(1):124 PMID: 35145192
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 421.46 |
| Cas No. | 147511-69-1 |
| Formula | C25H24FNO4 |
| Solubility | ≥10.56 mg/mL in H2O with ultrasonic; ≥14.35 mg/mL in DMSO; ≥8.46 mg/mL in EtOH with ultrasonic |
| Chemical Name | (E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid |
| Canonical SMILES | O[C@H](C[C@@H](/C=C/c1c(-c(cc2)ccc2F)c(cccc2)c2nc1C1CC1)O)CC(O)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
