PF-431396
Catalog No.
A8692
Pyk2 and FAK inhibitor
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PF-431396 is a potent and highly selective pyrimidine-based inhibitor of both Pyk2 and FAK, Consistent with the idea that the tyrosine phosphorylation of Pyk2 and FAK involves an initial autophosphorylation or transphosphorylation step, treating A20 cells.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 506.5 |
| Cas No. | 717906-29-1 |
| Formula | C22H21F3N6O3S |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥18.1 mg/mL in DMSO |
| Chemical Name | N-methyl-N-[2-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide |
| SDF | Download SDF |
| Canonical SMILES | CN(C1=CC=CC=C1CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
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