Latrunculin B
Catalog No.
C5804
F-actin–destabilizing agent
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Latrunculin B (CAS 76343-94-7) is a cell-permeable inhibitor of actin polymerization, which functions by directly binding to monomeric G-actin in a 1:1 ratio, thus preventing actin filament assembly. Although slightly less potent than latrunculin A, latrunculin B exhibits comparable short-term efficacy. Notably, its inhibitory effect rapidly diminishes in serum-containing media. Due to its transient mode of action, latrunculin B is particularly useful in short-duration cellular studies investigating actin dynamics, cytoskeletal organization, and related physiological processes.
| Physical Appearance | Colourless film |
| Storage | Store at -20°C |
| M.Wt | 395.5 |
| Cas No. | 76343-94-7 |
| Formula | C20H29NO5S |
| Solubility | ≤25mg/ml in DMSO |
| Chemical Name | 4R-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-2-thiazolidinone |
| SDF | Download SDF |
| Canonical SMILES | C/C(CC/C=C\[C@@H](C)CC[C@@H]1C[C@@H]2C[C@@]([C@H]3N([H])C(SC3)=O)(O)O1)=C/C(O2)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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-
Purity ≥ 97.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
Related Biological Data
