Toggle Nav
APExBIO

GW843682X

In stock
Catalog No.
A3456
PLK1/PLK3 inhibitor,potent and selective
Grouped product items
SizePriceStock Qty
5mg
$91.00
In stock
10mg
$143.00
In stock
50mg
$595.00
In stock

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

GW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively). GW843682X displays > 100-fold selectivity over ~30 other kinases tested including cdk1 and cdk2. GW843682X inhibits proliferation of most tumor cells in vitro and is selective over normal diploid fibroblasts.

Physical Appearance

Pale yellow solid

Chemical Properties

StorageStore at -20°C
M.Wt477.46
Cas No.660868-91-7
FormulaC22H18F3N3O4S
SynonymsGW 843682X;GW843682;GW-843682X
SolubilitySoluble in DMSO
Chemical Name5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide
SDFDownload SDF
Canonical SMILESCOC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

GW843682X