Giredestrant
Catalog No.
BA9213
Giredestrant (GDC-9545) is a nonsteroidal estrogen receptor (ER) ligand, orally effective, selective antagonist.
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Giredestrant (GDC-9545) is an orally potent, selective antagonist of the nonsteroidal estrogen receptor (ER) ligand.Giredestrant competes for binding to estradiol within the ER ligand binding domain and induces conformational changes.Giredestrant has antitumor activity.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 522.55 |
| Cas No. | 1953133-47-5 |
| Formula | C27H31F5N4O |
| Synonyms | GDC-9545;RG6171 |
| Solubility | ≥50.7 mg/mL in DMSO; ≥51.4 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol |
| SDF | Download SDF |
| Canonical SMILES | OCC(F)(F)CN([C@@H]1C2=C(F)C=C(NC3CN(CCCF)C3)C=C2F)[C@H](C)CC4=C1NC5=C4C=CC=C5 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
