Fedratinib hydrochloride hydrate
Catalog No.
A9916
A JAK2 inhibitor
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Fedratinib hydrochloride hydrate is an oral, bioavailable tyrosine kinase inhibitor that selectively inhibits Janus kinase 2 (JAK2) and FMS-like tyrosine kinase 3 (FLT3), thereby blocking signaling pathways associated with these kinases. Reduce the proliferation and survival of abnormal cells. It is mainly used in the treatment of myeloproliferative diseases such as myelofibrosis.
| Storage | Dry at -20°C for 2 years. |
| M.Wt | 615.62 |
| Cas No. | 1374744-69-0 |
| Formula | C27H40Cl2N6O4S |
| Solubility | insoluble in DMSO; insoluble in EtOH; insoluble in H2O |
| Chemical Name | N-(tert-butyl)-3-((5-methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)amino)benzenesulfonamide dihydrochloride hydrate |
| SDF | Download SDF |
| Canonical SMILES | CC1=CN=C(NC2=CC=C(OCCN3CCCC3)C=C2)N=C1NC4=CC(S(NC(C)(C)C)(=O)=O)=CC=C4.[H]O[H].[H]Cl.[H]Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
