• We specialize in small molecule inhibitors, agonists, antagonists and screening libraries!
Search Site
Home >> Signaling Pathways >> Chromatin/Epigenetics >> JAK >> 1,2,3,4,5,6-Hexabromocyclohexane
Related Products
1,2,3,4,5,6-Hexabromocyclohexane
JAK2 tyrosine kinase inhibitor

1,2,3,4,5,6-Hexabromocyclohexane

Catalog No. A4510
Size Price Stock Qty
10mM (in 1mL DMSO) $50.00 In stock
50mg $106.00 In stock

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

1,2,3,4,5,6-Hexabromocyclohexane

1,2,3,4,5,6-Hexabromocyclohexane Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

1,2,3,4,5,6-Hexabromocyclohexane Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Chemical Properties

Cas No. 1837-91-8 SDF Download SDF
Chemical Name 1,2,3,4,5,6-hexabromocyclohexane
Canonical SMILES C1(C(C(C(C(C1Br)Br)Br)Br)Br)Br
Formula C6H6Br6 M.Wt 557.54
Solubility >8.21mg/mL in DMSO Storage Store at RT
General tips N/A
Shipping Condition N/A

Background

Potently and directly inhibits JAK2 tyrosine kinase autophosphorylation, specifically inhibiting ligand-dependent JAK2 activation. A 16-hour treatment with 1 μM of compound reduces JAK2 tyrosine autophosphorylation levels to ~ 50% while 50 μM elimates nearly all JAK2 activity. Non-cytotoxic at 100 μM.