EN6
Catalog No.
BA3591
EN6 is a small molecule in vivo autophagy activator that covalently targets cysteine 277 in the subunit of lysosomal enzymes.
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EN6 is a small-molecule in vivo autophagy activator that covalently targets cysteine 277 in the subunit of the lysosomal enzyme.277 EN6-mediated modifications couple the enzyme to uncoupling, resulting in inhibition of signaling, increased lysosomal acidification, and activation of autophagy.EN6 also removes aggregates (the causative agent of frontotemporal dementia) in a lysosome-dependent manner.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 368.34 |
| Cas No. | 1808714-73-9 |
| Formula | C19H14F2N4O2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |