CD38 inhibitor 1
Catalog No.
B8752
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CD38 inhibitor 1 (CAS: 1700637-55-3) is a potent, selective small molecule inhibitor targeting CD38 enzymatic activity in human and mouse systems. Reported IC50 values are approximately 7.3 nM for human CD38 and 1.9 nM for mouse CD38. CD38 is implicated in intracellular calcium signaling and NAD+ metabolic regulation. Blocking CD38 enzymatic function enables exploration of its biological roles and potential therapeutic relevance in immunological processes, inflammation, autoimmune disorders, and cancer metabolism through both in vitro and in vivo studies.
| Storage | Store at -20°C |
| M.Wt | 413.54 |
| Cas No. | 1700637-55-3 |
| Formula | C22H27N3O3S |
| Solubility | ≥38.5 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
| Chemical Name | 4-(((1r,4r)-4-(2-methoxyethoxy)cyclohexyl)amino)-1-methyl-6-(thiazol-5-yl)quinolin-2(1H)-one |
| SDF | Download SDF |
| Canonical SMILES | CN(C1=C(C(N[C@@H]2CC[C@@H](OCCOC)CC2)=C3)C=C(C4=CN=CS4)C=C1)C3=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
