Bikinin
Catalog No.
B4898
GSK3 inhibitor and Brassinosteroid activator
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Bikinin (CAS 188011-69-0) is a small molecule inhibitor targeting glycogen synthase kinase 3 (GSK3)-like kinases, particularly BIN2, thereby activating brassinosteroid (BR) signaling pathways downstream of the BRI1 receptor. BR signaling regulates plant developmental processes, including stem elongation, vascular cell differentiation, leaf expansion, and stress responses. Treatment with Bikinin can phenotypically rescue BR-insensitive mutants in Arabidopsis by restoring BR-dependent gene expression. Additionally, Bikinin usage promotes xylem cell differentiation in Nicotiana benthamiana leaf disk culture, suggesting utility across different biological models.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 273.08 |
| Cas No. | 188011-69-0 |
| Formula | C9H9BrN2O3 |
| Solubility | insoluble in H2O; ≥13.65 mg/mL in DMSO; ≥2.4 mg/mL in EtOH |
| Chemical Name | 4-((5-bromopyridin-2-yl)amino)-4-oxobutanoic acid |
| SDF | Download SDF |
| Canonical SMILES | BrC1=CN=C(NC(CCC(O)=O)=O)C=C1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
