Zotatifin
Catalog No.
BA2258
Zotatifin (eFT226) is a potent, selective and well-tolerated eIF4A inhibitor.
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Zotatifin (eFT226) is a potent, selective and well-tolerated inhibitor of eIF4A.Zotatifin promotes the binding of eIF4A to specific mRNA sequences with recognition motifs in the 5'-UTRs (=2nM) and interferes with the assembly of the eIF4F initiation complex.Zotatifin exhibits potent antiviral effects that by inhibiting biosynthesis, thereby effectively reducing viral infectivity (=37nM).Zotatifin induces apoptosis.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 487.55 |
| Cas No. | 2098191-53-6 |
| Formula | C28H29N3O5 |
| Synonyms | eFT226 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |