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WHI-P180 EGFR/Janus Kinase 3 inhibitor

Catalog No.A8643
Size Price Stock Qty
5mg
$175.00
In stock
10mg
$266.00
In stock
50mg
$630.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & MSDS

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Chemical structure

WHI-P180

WHI-P180 Dilution Calculator

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Chemical Properties

Cas No. 211555-08-7 SDF Download SDF
Chemical Name 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Canonical SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC
Formula C16H15N3O3 M.Wt 297.31
Solubility Soluble in DMSO Storage Store at -20°C
Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

WHI-P180 is a potent inhibitors [with IC50 = 4.0 microM for epidermal growth factor receptor (EGFR) kinase inhibition] of the EGFR tyrosine kinase as well as Janus Kinase 3. Besides, WHI-P180 is a potent inhibitor of lgE-mediated mast cell responses to al