VNPP433-3β
Catalog No.
BA6511
VNPP433-3β is a molecular gel degrader that targets androgen receptor and its splice variants and serine/threonine protein kinases that interact with MAP kinase.
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VNPP433-3β is a molecular gel degrader that targets androgen receptor and its splice variants and serine/threonine protein kinases interacting with MAP kinase.VNPP433-3β inhibited the proliferation of cancer cells LNCaP, C4-2B, and CWR22Rv1, with a GI of 0.2, 0.3, and 0.31 μM, respectively.VNPP433-3β exhibited good pharmacokinetics in CD-1 mice showed good pharmacokinetic profile and inhibited CWR22Rv1 tumor growth in a xenograft mouse model.
| Physical Appearance | A solid |
| Storage | 4°C, protect from light |
| M.Wt | 438.61 |
| Cas No. | 1630820-51-7 |
| Formula | C29H34N4 |
| Synonyms | Galeterone 3β-imidazole |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |