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Trimetrexate

Catalog No.
BA1023
Trimetrexate (CI-898) is an antibiotic and a potent, orally active dihydrofolate reductase inhibitor.
Grouped product items
SizePriceStock Qty
1mL(10 mM in DMSO)
$217.00
Ship with 10-15 days
5mg
$198.00
Ship with 10-15 days
10mg
$360.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Trimetrexate (CI-898) is an antibiotic and a potent, orally active dihydrofolate reductase inhibitor that reduces the production of DNA and RNA precursors and leads to cell death, with 4.74 nM and 1.35 nM against human DHFR and Toxoplasma gondii DHFR, respectively.Trimetrexate also inhibits a wide range of cancer cell growth.Trimetrexate can be used in studies of Pneumocystis carinii pneumonia (PCP) and cancer.

Chemical Properties

Physical AppearanceA solid
Storage-20°C
M.Wt369.42
Cas No.52128-35-5
FormulaC19H23N5O3
SynonymsCI-898
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.