TPE-MI
Catalog No.
BA2044
TPE-MI (Tetraphenylethenemaleimide) is intrinsically non-fluorescent before binding to thiols via maleimide.
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TPE-MI (Tetraphenylethenemaleimide) is intrinsically non-fluorescent until it binds to thiols via maleimide.TPE-MI fluorescence is activated upon labeling of free cysteine thiols, which are normally buried in the core of globular proteins exposed upon unfolding.TPE-MI can be used to measure cellular unfolded protein load.TPE -MI can report imbalances in protein homeostasis in the Huntington's disease induced pluripotent stem cell model, as well as in cells transfected with mutant Huntington exon 1 prior to the formation of visible aggregates.TPE-MI also detects protein damage after dihydroartemisinin studies of malaria parasites.
| Physical Appearance | A solid |
| Storage | 4°C, protect from light |
| M.Wt | 441.52 |
| Cas No. | 1245606-71-6 |
| Formula | C31H23NO2 |
| Synonyms | Tetraphenylethene maleimide |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |