SZM679
Catalog No.
BA3512
SZM679 is an orally potent and selective inhibitor with values of 8.6 nM and >5000 nM for RIPK1 and RIPK3, respectively.
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SZM679 is an orally potent and selective inhibitor of RIPK1 and RIPK3 with values of 8.6 nM and >5000 nM, respectively.SZM679 reverses tumor necrosis factor-induced systemic inflammatory responses.SZM679 reduces hyperphosphorylation of Tau proteins, neuroinflammation, and levels of RIPK1 phosphorylation in the hippocampus and cortex.SZM679 is useful for Alzheimer's disease (AD) research.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 591.51 |
| Cas No. | 3027645-52-6 |
| Formula | C27H18F5N3O5S |
| Chemical Name | N-(5-fluoro-6-(4-fluoro-3-(2-(3-(trifluoromethoxy)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)-3-oxocyclobutane-1-carboxamide |
| Canonical SMILES | O=C(C1CC(C1)=O)NC2=NC3=CC(F)=C(OC4=CC=C(F)C(NC(CC5=CC=CC(OC(F)(F)F)=C5)=O)=C4)C=C3S2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |