Sunvozertinib
Catalog No.
BA6331
Sunvozertinib (DZD9008) is a potent (EGFR, Her2, especially mutant) inhibitor.
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Sunvozertinib (DZD9008) is a potent (EGFR, Her2, and especially mutant) inhibitor.Sunvozertinib displays exon 20NPH insertion, EGFR exon 20ASV insertion, EGFRL858R and T790M mutations, and Her2 exons 20YVMA and WTA431 of 20.4, 20.4, 1.1, 7.5 and 80.4 nM, respectively.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 584.08 |
| Cas No. | 2370013-12-8 |
| Formula | C29H35ClFN7O3 |
| Synonyms | DZD9008 |
| Solubility | ≥59 mg/mL in DMSO; ≥10.2 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | (R)-N-(5-((4-((5-chloro-4-fluoro-2-(2-hydroxypropan-2-yl)phenyl)amino)pyrimidin-2-yl)amino)-2-(3-(dimethylamino)pyrrolidin-1-yl)-4-methoxyphenyl)acrylamide |
| Canonical SMILES | C=CC(NC1=C(N2C[C@H](N(C)C)CC2)C=C(OC)C(NC3=NC=CC(NC4=C(C(C)(O)C)C=C(F)C(Cl)=C4)=N3)=C1)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
