Sulisobenzone

Sulisobenzone (CAS No.: 4065-45-6) is a benzophenone ultraviolet filter widely used in biomedical research and drug development. Its role in biological systems is known for its properties as an endocrine disruptor, particularly in interfering with endocrine function and energy metabolism. In addition, it affects nucleotide synthesis and oxidative stress responses. Studies have shown that Sulisobenzone affects thyroid hormone biosynthesis and induces oxidative stress, providing a basis for further investigation of its mechanistic pathways in various biological contexts. In experimental settings, Sulisobenzone has been observed to reduce ultraviolet-induced skin erythema and cancer formation, as demonstrated in albino mouse models. Its in vitro activity levels are typically in the nanomolar to micromolar range, depending on the specific experimental setup and research focus. Sulisobenzone is widely used in cell assays and animal models to elucidate the mechanisms of endocrine and oxidative stress pathways. The concentrations or doses used in studies are generally adjusted according to experimental objectives to ensure precise investigation of its biological effects while avoiding any implication of human therapeutic applications.