Senktide
Catalog No.
B6580
NK3 tachykinin receptor agonist
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Senktide (CAS 106128-89-6) is a peptide-based small molecule acting as a selective agonist at neurokinin NK3 receptors. NK3 receptors are expressed widely within the central nervous system and peripheral tissues, where they regulate neurotransmitter release, endocrine responses, and nociceptive signaling. Through activation of NK3 receptors, Senktide facilitates investigation into neuronal signaling pathways, stress responses, and hormone secretion mechanisms. In biomedical research, Senktide serves as a valuable pharmacological tool for elucidating NK3-mediated physiological processes and exploring therapeutic potential.
| Physical Appearance | A crystalline solid |
| Storage | Desiccate at -20°C |
| M.Wt | 841.97 |
| Cas No. | 106128-89-6 |
| Formula | C40H55N7O11S |
| Solubility | ≥53.7 mg/mL in DMSO; ≥54.6 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid |
| SDF | Download SDF |
| Canonical SMILES | O=C([C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC(CCC(O)=O)=O)=O)N(C)[C@H](C(NCC(N[C@H](C(N[C@H](C(N)=O)CCSC)=O)CC(C)C)=O)=O)CC2=CC=CC=C2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
