RMC-6291
Catalog No.
BA2754
RMC-6291 is an orally effective covalent inhibitor.
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RMC-6291 is an orally effective covalent inhibitor.RMC-6291 forms a triple complex between KRAS(ON) and cyclophilin A (CypA) in tumor cells. Thus, RMC-6291 prevents KRAS(ON) from signaling by spatially blocking effector binding.RMC-6291 inhibits the signaling pathway and induces apoptosis in KRAS mutant H358 cells.RMC-6291 also inhibits the proliferation of KRAS mutant cells at a median of 0.11 nM.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 1012.26 |
| Cas No. | 2641998-63-0 |
| Formula | C55H78FN9O8 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |