Ritonavir-13CD3
Catalog No.
SL1062
13C- and deuterium-labeled Ritonavir
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Ritonavir-13C, D3 is a stable isotope-labeled form of Ritonavir, containing carbon-13 and deuterium (hydrogen-2) labels. Ritonavir is an HIV protease inhibitor widely used in the treatment of HIV infection and AIDS. In addition, Ritonavir has been found to inhibit the SARS-CoV 3CLpro protease, with an IC50 value of 1.61 μM. (medchemexpress.cn) In biomedical research, Ritonavir-13C, D3 is commonly used as a tracer, or as an internal standard in nuclear magnetic resonance (NMR), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS) analyses to enable quantitative analysis of Ritonavir. The dose or concentration used in experiments typically depends on the experimental design and research objectives. Stable isotope-labeled compounds play an important role in pharmacokinetic studies, providing highly sensitive and highly specific detection results.
| Storage | Store at -20°C |
| M.Wt | 724.96 |
| Cas No. | 155213-67-5 (unlabelled) |
| Formula | C3613CH45D3N6O5S2 |
| Chemical Name | thiazol-5-ylmethyl ((2S,3S,5S)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-(methyl-13C-d3)ureido)-3-methylbutanamido)-1,6-diphenylhexan-2-yl)carbamate |
| SDF | Download SDF |
| Canonical SMILES | CC(C)[C@H](NC(N([13C]([2H])([2H])[2H])CC1=CSC(C(C)C)=N1)=O)C(N[C@H](C[C@H](O)[C@@H](NC(OCC2=CN=CS2)=O)CC3=CC=CC=C3)CC4=CC=CC=C4)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |