(R)-(-)-Apomorphine hydrochloride
Catalog No.
B6936
Prototypical dopamine agonist
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(R)-(-)-Apomorphine hydrochloride (CAS 314-19-2) is a non-selective agonist at dopamine receptors, displaying affinity for human recombinant dopamine receptor subtypes D1 (pKi 6.43), D2L (pKi 7.08), D3 (pKi 7.59), D4 (pKi 8.36), and D5 (pKi 7.83). It has biphasic modulatory effects on locomotion and demonstrates antiparkinsonian and neuroprotective activities. It is employed extensively in neuroscience research for investigating dopamine-related mechanisms and therapeutic strategies in Parkinson's disease models.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 303.79 |
| Cas No. | 314-19-2 |
| Formula | C17H17NO2·HCl |
| Solubility | ≥1.08 mg/mL in EtOH with ultrasonic; ≥12.9 mg/mL in DMSO; ≥5.12 mg/mL in H2O |
| Chemical Name | (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride |
| SDF | Download SDF |
| Canonical SMILES | OC1=C2C3=C([C@](CC2=CC=C1O)([H])N(C)CC4)C4=CC=C3.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
Related Biological Data
