Pregabalin-d4

Pregabalin-d4 (CAS No.: 1276197-54-6) is the stable isotope-labeled counterpart of Pregabalin, mainly used in biomedical research and drug development. Pregabalin is a γ-aminobutyric acid (GABA) analog that, as an anticonvulsant, binds to the α?δ subunit of voltage-dependent calcium channels to inhibit calcium ion influx, thereby reducing neurotransmitter release and achieving analgesic and anticonvulsant effects. The isotope-labeling properties of Pregabalin-d4 make it important in pharmacokinetic studies, especially in mass spectrometry analysis, where it can be used to trace the metabolic pathways of the drug in vivo and for quantitative analysis. Since the in vitro activity level of Pregabalin is typically in the nanomolar to micromolar range, the working concentration and dose of Pregabalin-d4 in related experiments usually depend on the specific experimental design and research objectives.