PF-6274484
Catalog No.
BA6347
PF-6274484 was a potent inhibitor with s of 0.14 nM and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.
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PF-6274484 was a potent inhibitor for EGFR-L858R/T790M and WT-EGFR, with s of 0.14 nM and 0.18 nM, respectively.PF-6274484 inhibited EGFR-L858R/T790M autophosphorylation and EGFR-WT in H1975 tumor cells and A549 tumor cells, with an IC of 6.6 and 5.8 nM, respectively.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 372.78 |
| Cas No. | 1035638-91-5 |
| Formula | C18H14ClFN4O2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |