pentetate calcium trisodium hydrate

pentetate calcium trisodium hydrate (CAS No.: 207226-35-5) is a synthetic aminopolycarboxylate metal chelator in the diethylenetriaminepentaacetic acid class that is widely categorized as a chemical biology and toxicology research reagent for studying metal ion sequestration and metal dependent cellular responses, with functional activity primarily arising from high affinity coordination of polyvalent metal cations and consequent modulation of labile metal pools rather than direct receptor agonism or enzyme active site blockade, and reported research evidence indicates utility as a broad chelation tool including iron associated systems and other heavy metal contexts while also being described in experimental virology literature as a nontoxic inhibitor of cytomegalovirus replication, supporting its use in mechanistic studies that examine links between metal availability, oxidative stress related signaling, and host cell permissiveness to viral replication pathways; because robust target resolved potency datasets are limited and context dependent for this specific hydrate form, in vitro effects are generally interpreted within concentration windows spanning low micromolar to higher micromolar ranges depending on cell type, metal burden, and assay endpoint, and it is commonly applied in cultured cell models, ex vivo preparations, and exploratory animal research paradigms to probe metal detoxification biology, redox associated injury mechanisms, and chelation sensitive phenotypes, with the concentrations or doses used in experiments typically depending on specific experimental designs and research objectives, making it suitable for hit validation support, pathway deconvolution, and comparative screening workflows in biomedical research and early stage drug discovery settings that require a well characterized non clinical chelation reference compound.