Paclitaxel-d5
Catalog No.
SL1060
A stable isotope deuterated compound of Paclitaxel
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Paclitaxel-d5 is the stable isotope-labeled counterpart of Paclitaxel. By introducing five deuterium atoms into the molecule, it is distinguished from the unlabeled molecule. As a natural antitumor drug, Paclitaxel primarily stabilizes tubulin polymerization, leading to mitotic arrest and induction of apoptosis, ultimately resulting in cell death. In biomedical research, Paclitaxel-d5 is commonly used in metabolism studies, pharmacokinetic analysis, and as an internal standard in mass spectrometry analysis to improve detection sensitivity and accuracy. The dose or concentration used in experiments typically depends on the experimental design and research objectives.
| Storage | Store at -20°C |
| M.Wt | 858.94 |
| Cas No. | 1129540-33-5 |
| Formula | C47H46D5NO14 |
| Chemical Name | (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-(benzamido-2,3,4,5,6-d5)-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,1 |
| SDF | Download SDF |
| Canonical SMILES | O=C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])N[C@@H](C2=CC=CC=C2)[C@H](C(O[C@@H]3C(C)=C([C@@H](OC(C)=O)C([C@@]4(C)[C@]([C@@](CO5)(OC(C)=O)[C@@]5([H])C[C@@H]4O)([H])[C@@H]6OC(C7=CC=CC=C7)=O)=O)C(C)(C)[C@@]6(O)C3)=O)O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |