Oseltamivir-13CD3 acid

Oseltamivir-13C, D3 acid is a stable isotope-labeled compound of Oseltamivir acid. Oseltamivir acid is the active metabolite of Oseltamivir phosphate, and its primary target is influenza virus neuraminidase. By inhibiting the activity of this enzyme, it prevents the release and spread of the virus in host cells. Studies show that the IC50 values of Oseltamivir acid against influenza viruses A/H3N2, A/H1N2, A/H1N1, and type B are 0.67, 0.9, 1.34, and 13 nM, respectively, indicating potent in vitro inhibitory activity in the nanomolar to low-nanomolar range. In cell and animal models, Oseltamivir acid is widely used to evaluate anti-influenza efficacy, and the doses or concentrations used in experiments typically depend on the experimental design and research objectives. As a stable isotope-labeled compound of Oseltamivir acid, Oseltamivir-13C, D3 acid can be used for pharmacokinetic studies, metabolic pathway tracing, and as an internal standard in mass spectrometry analysis, helping to improve detection sensitivity and accuracy.