NS383
Catalog No.
BA6987
NS383 is a potent and unique selective rat inhibitor containing 1a and/or 3 subunits.
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NS383 is a potent and uniquely selective rat inhibitor containing 1a and/or 3 subunits.NS383 inhibits H(+) activation currents recorded from homopolymerized ASIC1a, ASIC3, and heteropolymerized ASIC1a+3 in rats, with values ranging from 0.61 to 2.2 μM.NS383 is well-tolerated and is capable of reversing pathologically pain-like behaviors, possibly through peripheral actions, but also through actions within the central pain circuit. but also possibly through actions within central pain circuits.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 321.37 |
| Cas No. | 309711-59-9 |
| Formula | C19H19N3O2 |
| Solubility | ≥6.48 mg/mL in DMSO with ultrasonic; insoluble in EtOH; insoluble in H2O |
| Chemical Name | (Z)-8-ethyl-3-(hydroxyimino)-5-phenyl-1,3,6,7,8,9-hexahydro-2H-pyrrolo[3,2-h]isoquinolin-2-one |
| Canonical SMILES | O=C1NC2=C(CN(CC3)CC)C3=C(C4=CC=CC=C4)C=C2/C1=N/O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
