NB-598 Maleate
Catalog No.
A3647
Squalene epoxidase inhibitor
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NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 565.74 |
| Cas No. | 155294-62-5 |
| Formula | C31H35NO5S2 |
| Synonyms | NB598 Maleate;NB 598 Maleate |
| Solubility | ≥16.5 mg/mL in DMSO |
| Chemical Name | (Z)-but-2-enedioic acid;(E)-N-ethyl-6,6-dimethyl-N-[[3-[(4-thiophen-3-ylthiophen-2-yl)methoxy]phenyl]methyl]hept-2-en-4-yn-1-amine |
| SDF | Download SDF |
| Canonical SMILES | CCN(CC=CC#CC(C)(C)C)CC1=CC(=CC=C1)OCC2=CC(=CS2)C3=CSC=C3.C(=CC(=O)O)C(=O)O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
