N1-Propyl-Pseudo-UTP

N1-Propyl-Pseudo-UTP is a modified pseudouridine triphosphate featuring a propyl group at the N1 position. This modification significantly alters the chemical properties and biological functions of the nucleotide. During in vitro transcription reactions, N1-Propyl-Pseudo-UTP can be incorporated into RNA molecules, producing RNA containing N1-propyl pseudouridine. Such modified RNA plays an important role in studying RNA structure, function, and interactions with proteins. In addition, N1-Propyl-Pseudo-UTP markedly enhances RNA stability and reduces its degradation within cells. Consequently, this modification has wide-ranging applications in gene expression research, RNA therapeutic development, and gene therapy.

lithium (5-(2,4-dioxo-1-propyl-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate

C₁₂H₂₁N₂O₁₅P₃ (free acid)

Store at -20°C or below