MS9449
Catalog No.
BA6384
MS9449 was an effective degrader with 17 nM and 10 nM for wild-type and mutant L858R, respectively.
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MS9449 is a potent degrader of wild-type and mutant L858R at 17 nM and 10 nM, respectively.MS9449 efficiently induces the degradation of mutant EGFRs through the ubiquitin/proteasome system (UPS) and autophagy/lysosomal pathways.MS9449 has a strong inhibitory effect on the proliferation of NSCLC cells.MS9449 can be used in anticancer research.
| Storage | -20°C |
| M.Wt | 1151.82 |
| Cas No. | 2772612-96-9 |
| Formula | C60H76ClFN10O8S |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |