MK-8353
Catalog No.
BA6431
MK-8353 (SCH900353) is a potent, selective, orally available inhibitor.
Featured Products
MK-8353 (SCH900353) is a potent, selective, orally available inhibitor with values of 23.0 nM and 8.8 nM, respectively; MK-8353 has antitumor activity.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 691.84 |
| Cas No. | 1184173-73-6 |
| Formula | C37H41N9O3S |
| Synonyms | SCH900353 |
| Solubility | ≥52.1 mg/mL in DMSO; ≥17.07 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (S)-N-(3-(6-isopropoxypyridin-3-yl)-1H-indazol-5-yl)-1-(2-(4-(4-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)-3,6-dihydropyridin-1(2H)-yl)-2-oxoethyl)-3-(methylthio)pyrrolidine-3-carboxamide |
| Canonical SMILES | CN1C=NC(C2=CC=C(C=C2)C3=CCN(CC3)C(CN4CC[C@](C(NC5=CC6=C(C=C5)NN=C6C7=CC=C(N=C7)OC(C)C)=O)(SC)C4)=O)=N1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure








