KT 5823
Catalog No.
B6673
protein kinase G inhibitor
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KT 5823 (CAS 126643-37-6) is a selective inhibitor of protein kinase G (PKG). By specifically inhibiting PKG-mediated phosphorylation pathways, KT 5823 serves as an important pharmacological tool in biomedical research for dissecting the role of PKG signaling in various physiological and pathological contexts. Researchers utilize KT 5823 extensively to investigate PKG-dependent processes, including vascular tone regulation, platelet aggregation, neuronal signaling, and smooth muscle function.
| Physical Appearance | A neat oil |
| Storage | Desiccate at -20°C |
| M.Wt | 495.53 |
| Cas No. | 126643-37-6 |
| Formula | C29H25N3O5 |
| Solubility | Soluble in DMSO |
| Chemical Name | (5S,6S,8S)-methyl 6-methoxy-5,14-dimethyl-13-oxo-6,7,8,13,14,15-hexahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacene-6-carboxylate |
| SDF | Download SDF |
| Canonical SMILES | O=C([C@@]([C@]1(C)O[C@@H]2N3C4=C5N1C6=CC=CC=C6C5=C(CN(C)C7=O)C7=C4C8=CC=CC=C38)(C2)OC)OC |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity ≥95.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
