JH-RE-06
Catalog No.
BA3978
JH-RE-06
Featured Products
JH-RE-06, a potent intercalation inhibitor (=0.78 μM; =0.42 μM), targets REV1, which interacts with the REV7 subunit of POLζ.JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.JH-RE-06 improves the efficacy of chemotherapy.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 468.72 |
| Cas No. | 1361227-90-8 |
| Formula | C20H16Cl3N3O4 |
| Solubility | ≥16.47 mg/mL in DMSO; ≥2.87 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | 8-chloro-2-((2,4-dichlorophenyl)amino)-3-(3-methylbutanoyl)-5-nitroquinolin-4(1H)-one |
| Canonical SMILES | O=C1C(C(CC(C)C)=O)=C(NC2=C(Cl)C=C(Cl)C=C2)NC3=C1C([N+]([O-])=O)=CC=C3Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
