Toggle Nav

Jervine

Catalog No.
A8656
Hedgehog signaling Inhibitor
Grouped product items
SizePriceStock Qty
5mg
$174.00
Ship with 10-15 days
10mg
$314.00
Ship with 10-15 days
50mg
$1,256.00
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Inhibitor of Hedgehog signaling (IC50 = 500 - 700 nM); binds directly to Smoothened (Smo). Inhibits the response of target tissues to Sonic hedgehog signaling, possibly via the sterol sensing domain of Patched. Teratogenic.

Chemical Properties

Physical AppearanceWhite solid
StorageStore at -20°C
M.Wt425.6
Cas No.469-59-0
FormulaC27H39NO3
SolubilityLimited solubility, soluble in DMSO or ethanol
Chemical Name(3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one
SDFDownload SDF
Canonical SMILESCC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Jervine