IMT1
Catalog No.
BA3957
IMT1 is the first, specific and non-competitive inhibitor of human mitochondrial RNA polymerase.
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IMT1 is a first-of-its-kind, specific and non-competitive inhibitor of human mitochondrial RNA polymerase.IMT1 induces conformational changes in POLRMT, thereby blocking substrate binding and transcription in vitro in a dose-dependent manner.IMT1 decreases deoxynucleoside triphosphate levels and citric acid cycle intermediates, leading to significant depletion of cellular amino acid levels.IMT1 has potential for use in mitochondrial transcription and other related diseases.
Physical Appearance | A solid |
Storage | -20°C |
M.Wt | 351.40 |
Cas No. | 2304621-31-4 |
Formula | C21H21NO4 |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |