Imlunestrant
Catalog No.
BA9222
Immunestrant (LY-3484356) is an orally effective and selective estrogen receptor degrader (SERD) with pure antagonistic properties.
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Immunestrant (LY-3484356) is an orally effective and selective estrogen receptor degrader (SERD) with pure antagonistic properties.Immunestrant sustainably inhibits ER-dependent gene transcription and cell growth.Immunestrant can be used in ER-positive (ER+) advanced breast cancer (aBC) and endometrial endometrioid carcinoma (EEC).
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 524.51 |
| Cas No. | 2408840-26-4 |
| Formula | C29H24F4N2O3 |
| Synonyms | LY-3484356 |
| Solubility | ≥57 mg/mL in DMSO; ≥49.5 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (R)-5-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-8-(trifluoromethyl)-5H-chromeno[4,3-c]quinolin-2-ol |
| Canonical SMILES | OC1=CC2=NC=C3C([C@](C4=CC=C(OCCN5CC(CF)C5)C=C4)([H])OC6=CC(C(F)(F)F)=CC=C63)=C2C=C1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
