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IDO inhibitor 1

Catalog No.
A3483
Indoleamine-2,3-dioxygenase inhibitor
Grouped product items
SizePriceStock Qty
5mg
$233.00
In stock
10mg
$355.00
In stock
25mg
$514.00
In stock
50mg
$841.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value <100 nM.

IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system.

Reference:
[1].  Andrew P. Combs, et al. 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase. Patent Numeber: EP 2315756 A2
http://www. google.com/patents/EP2315756A2?cl=en

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt438.23
Cas No.1204669-37-3
Formula C11H13BrFN7O4S
Solubilityinsoluble in H2O; ≥19.35 mg/mL in DMSO; ≥34.75 mg/mL in EtOH with ultrasonic
Chemical Name(E)-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-((2-(sulfamoylamino)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide
SDFDownload SDF
Canonical SMILESBrC1=CC(/N=C(NO)\C2=NON=C2NCCNS(=O)(N)=O)=CC=C1F
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Chemical structure

IDO inhibitor 1