IDH889
Catalog No.
BA7853
IDH889 is an orally available, brain-permeable, variant- and mutation-specific inhibitor of isocitrate dehydrogenase.
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IDH889 is an orally available, brain-permeable, variant- and mutation-specific inhibitor of isocitrate dehydrogenase.IDH889 is highly selective for the R132* mutant phenotype, with values of 0.02 μM,0.072 μM and 1.38 μM for, IDH1 and action, respectively.IDH889 has a highly potent inhibitory effect on intracellular levels of 2-HG, with an IC value of 0.014 μM.
Physical Appearance | A solid |
Storage | -20°C |
M.Wt | 436.48 |
Cas No. | 1429179-07-6 |
Formula | C23H25FN6O2 |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |