ICA-105574
Catalog No.
BA6886
ICA-105574 is a potent channel activator.
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ICA-105574 is a potent channel activator.The primary mechanism by which ICA-105574 enhances hERG channel activity is by eliminating hERG channel inactivation.ICA-105574 dramatically enhances current amplitude by more than 10-fold, with a value of 0.5+/-0.1 μM and a Hill slope (n(H)) of 3.3+/-0.2.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 334.33 |
| Cas No. | 316146-57-3 |
| Formula | C19H14N2O4 |
| Solubility | ≥33.7 mg/mL in DMSO; ≥2.98 mg/mL in EtOH with ultrasonic; insoluble in H2O |
| Chemical Name | 3-nitro-N-(4-phenoxyphenyl)benzamide |
| Canonical SMILES | O=C(NC1=CC=C(OC2=CC=CC=C2)C=C1)C3=CC=CC([N+]([O-])=O)=C3 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
