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Helioxanthin

Catalog No.
B4699
novel inhibitor of HBV, HCV and HSV-1 virus
Grouped product items
SizePriceStock Qty
5mg
$383.00
Ship with 5-10 days
10mg
$549.00
Ship with 5-10 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Helioxanthin (ACH126447) is a novel inhibitor of HBV, HCV and HSV-1 virus with EC50 values of 1 μM, 3 μM and 2 μM, respectively [1].

Helioxanthin has shown significant antiviral effect on HBV, HCV and HSV-1 virus in vitro with EC50 values of 1 μM, 3 μM and 2 μM, respectively. In a cell culture model, the level of HBV RNA, the expression of HBV antigen and its replication were all reduced by helioxanthin. Besides, helioxanthin has been exhibited to have a low cytotoxicity on both MT-223 and CEM24 cell lines with ID50 values of 2.5 μM and 31 μM, respectively [1].

Reference:
[1] Yeo H1, Li Y, Fu L, Zhu JL, Gullen EA, Dutschman GE, Lee Y, Chung R, Huang ES, Austin DJ, Cheng YC. Synthesis and antiviral activity of helioxanthin analogues. J Med Chem. 2005 Jan 27;48(2):534-46.

Chemical Properties

StorageStore at -20°C
M.Wt348.31
Cas No.18920-47-3
FormulaC20H12O6
SolubilitySoluble in DMSO
SDFDownload SDF
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

Helioxanthin