GSK3494245
Catalog No.
BA2139
GSK3494245 (DDD01305143) is a potent, orally active
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GSK3494245 (DDD01305143) is a potent, orally active, selective inhibitor of chymotrypsin-like activity that binds parasite proteasomes at a site sandwiched between the β4 and β5 subunits (for WT proteasomes = 0.16 μM).GSK3494245 moderately inhibits the chymotrypsin-like activity of human proteasomes (IC:26S = 13 μM; IC = 40 μM for enriched THP-1 extract).GSK3494245 has good biosafety properties.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 410.44 |
| Cas No. | 2080410-41-7 |
| Formula | C21H23FN6O2 |
| Synonyms | DDD01305143 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |