GNE-274
Catalog No.
BA9233
GNE-274 is a structural analog of the ER degradant GDC-0927, a non-degradant.
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GNE-274 is a structural analog of the ER-degrading agent, GDC-0927, and is a nondegrading agent.GNE-274 does not induce ER conversion in breast cancer cell lines and functions as a partial agonist of ER.GNE-274 increases chromatin accessibility to the ER-DNA binding site, whereas GDC-0927 does not.GNE-274 is a potent ER ligand-binding domain (LBD) inhibitor.GNE-274 can be used in cancer research.
Physical Appearance | A solid |
Storage | 4°C, protect from light |
M.Wt | 457.56 |
Cas No. | 2369048-69-9 |
Formula | C29H31NO4 |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |