Framycetin
Catalog No.
BA1019
Framycetin (NeomycinB) is an aminoglycoside antibiotic that is a potent inhibitor of cleavage activity.
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Framycetin (NeomycinB) is an aminoglycoside antibiotic and a potent inhibitor of cleavage activity with a value of 35 μM.Framycetin competes for specific divalent metal ion binding sites in RNasePRNA.Framycetin inhibits Hammerhead Ribonuclease with a value of 13.5 μM.Framycetin is the 5 ″-azidoneomycinB precursor that binds to the Drosha site in miR-525 for hepatic encephalopathy and enteropathogenic E. coli infections.
| Physical Appearance | A liquid |
| Storage | -20°C |
| M.Wt | 614.64 |
| Cas No. | 119-04-0 |
| Formula | C23H46N6O13 |
| Synonyms | NeomycinB;FradiomycinB |
| Chemical Name | (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)ox |
| Canonical SMILES | O([C@H]1[C@H](O[C@H]2[C@H](O)[C@H](O[C@H]3O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H](CO)O2)[C@@H](O)[C@H](N)C[C@@H]1N)[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |