Filibuvir
Catalog No.
BA1874
Filibuvir is an orally effective, selective non-nucleoside inhibitor of the non-structural 5B protein RNA-dependent RNA polymerase (RdRp).
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Filibuvir is an orally effective, selective non-nucleoside inhibitor of the RNA-dependent RNA polymerase (RdRp) of the unstructured 5B protein.Filibuvir binds non-covalently to the thumb II variant pocket of NS5B.Filibuvir inhibits the replicon of two isoforms, the 1a and the 1b genotypes, both with an EC of 59 nM. Filibuvir preferentially inhibited elongated RNA synthesis and effectively reduced viral RNA accumulation.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 503.64 |
| Cas No. | 877130-28-4 |
| Formula | C29H37N5O3 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |