DS18561882
Catalog No.
BA7976
DS18561882 is a potent, highly selective inhibitor of methylenetetrahydrofolate dehydrogenase 2 for the enzyme.
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DS18561882 is a potent, highly enzyme-selective inhibitor of methylenetetrahydrofolate dehydrogenase 2 with a value of 0.0063 μM.DS18561882 inhibits MTHFD1 with a value of 0.57 μM.DS18561882 has good oral pharmacokinetic properties.
| Physical Appearance | A solid |
| Storage | 4°C |
| M.Wt | 608.63 |
| Cas No. | 2227149-22-4 |
| Formula | C28H31F3N4O6S |
| Solubility | ≥48.1 mg/mL in DMSO; ≥46.9 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (S)-N-(4-(8-(3,4-dimethylpiperazin-1-yl)-7-methyl-5-oxo-1,3,4,5-tetrahydro-2H-chromeno[3,4-c]pyridine-3-carbonyl)-2-(trifluoromethoxy)phenyl)methanesulfonamide |
| SDF | Download SDF |
| Canonical SMILES | CC1=C(OC(C2=C3CCN(C(C4=CC=C(NS(C)(=O)=O)C(OC(F)(F)F)=C4)=O)C2)=O)C3=CC=C1N5CCN(C)[C@@H](C)C5 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
