Doxapram HCl
Catalog No.
A8419
Potassium channel inhibitor
Featured Products
Doxapram HCl is a respiratory stimulant that exerts its biological effects by inhibiting the TASK subtype of two-pore potassium channels. Relevant electrophysiological experimental results indicate that this compound shows inhibitory activity against the TASK-1 channel, the TASK-3 channel, and the TASK-1/TASK-3 heterodimer, with concentration-dependent differences in its effects on the above channel subtypes. Therefore, Doxapram HCl can be used as a selective TASK channel blocker and is widely used to study the specific physiological roles and pathological significance of TASK channels in respiratory regulation, central nervous system function, and hypoxia-sensing mechanisms.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 432.98 |
| Cas No. | 7081-53-0 |
| Formula | C24H30N2O2·HCl·H2O |
| Solubility | ≥20.05 mg/mL in DMSO with gentle warming; ≥14.27 mg/mL in H2O with ultrasonic; ≥14.6 mg/mL in EtOH |
| Chemical Name | 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenylpyrrolidin-2-one hydrochloride hydrate |
| SDF | Download SDF |
| Canonical SMILES | CCN(CC(CCN1CCOCC1)C1(c2ccccc2)c2ccccc2)C1=O.O.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
Chemical structure
