Demethylasterriquinone B1
Catalog No.
B6869
insulin receptor (IR) activator
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Demethylasterriquinone B1 (CAS 78860-34-1) is a selective insulin receptor (IR) agonist that acts by promoting tyrosine phosphorylation within the insulin receptor β-subunit. This phosphorylation event subsequently activates downstream signaling pathways, particularly phosphatidylinositol 3-kinase (PI3K) and AKT. Demethylasterriquinone B1 has utility as a research tool for investigating insulin signaling cascades, glucose metabolism, and related metabolic regulatory mechanisms, thus facilitating studies aimed at understanding insulin sensitivity and metabolic diseases.
| Physical Appearance | A crystalline solid |
| Storage | Desiccate at -20°C |
| M.Wt | 506.59 |
| Cas No. | 78860-34-1 |
| Formula | C32H30N2O4 |
| Solubility | Soluble in DMSO |
| Chemical Name | 2,5-dihydroxy-3-(7-(3-methylbut-2-en-1-yl)-1H-indol-3-yl)-6-(2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl)cyclohexa-2,5-diene-1,4-dione |
| SDF | Download SDF |
| Canonical SMILES | OC(C1=O)=C(C(C(O)=C1C(C2=CC=C3)=CNC2=C3C/C=C(C)\C)=O)C4=C(C(C)(C=C)C)NC5=CC=CC=C45 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
