Cytochalasin C
Catalog No.
C4537
inhibits actin polymerization
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Cytochalasin C (CAS 22144-76-9) is a fungal metabolite known to inhibit actin polymerization. It acts by disrupting the assembly dynamics of actin filaments, promoting rapid initial filament formation but ultimately reducing steady-state polymerization. Compared to related analogs, cytochalasin C strongly accelerates early actin assembly and notably diminishes polymerization extent, although it exerts only mild shortening effects on established filaments. It is commonly utilized as an experimental tool to study actin-dependent cellular processes, including cell motility, phagocytosis, secretion, and growth regulation.
| Physical Appearance | A white powder |
| Storage | Store at -20°C |
| M.Wt | 507.6 |
| Cas No. | 22144-76-9 |
| Formula | C30H37NO6 |
| Solubility | Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide |
| Chemical Name | (3S,3aR,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(acetyloxy)-3,3a,6,6a,9,10,12,15-octahydro-6,12-dihydroxy-4,5,10,12-tetramethyl-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1,11(2H)-dione |
| SDF | Download SDF |
| Canonical SMILES | O[C@H]1[C@H]2[C@@]3([C@@H](/C=C/[C@@](C)(O)C([C@@H](C)C/C=C/2)=O)OC(C)=O)C([C@H](CC4=CC=CC=C4)NC3=O)C(C)=C1C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
