Brivudine
Catalog No.
BA1598
Thymidine analogs with antiviral activity for early acute herpes zoster.
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Brivudine is a nucleoside thymidine-structure analog that exerts antiviral activity by inhibiting viral DNA polymerase. Its metabolites competitively bind to viral DNA polymerase, thereby interfering with viral DNA synthesis and replication. Current research widely focuses on its potential applications in early acute varicella-zoster virus infection, and it can be used for experimental exploration of related viral replication mechanisms and viral inhibitory effects. It has certain experimental reference value in studies on antiviral drug development, biopharmaceutical screening, and elucidation of viral replication mechanisms.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 333.14 |
| Cas No. | 69304-47-8 |
| Formula | C11H13BrN2O5 |
| Synonyms | Bromovinyldeoxyuridine;BVDU |
| Solubility | ≥52.5 mg/mL in DMSO; ≥6.8 mg/mL in EtOH with ultrasonic; ≥2.59 mg/mL in H2O gentle warming and ultrasonic |
| Chemical Name | 5-((E)-2-bromovinyl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione |
| SDF | Download SDF |
| Canonical SMILES | OC[C@@H](O1)[C@@H](O)C[C@@H]1N(C=C(/C=C/Br)C(N2)=O)C2=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |